Semaglutide API Intermediate Supplier Manufacturer (Pharma Grade)

Semaglutide API Intermediate is a medication for the treatment of type 2 diabetes. Side effects include medullary thyroid cancer, kidney problems, diabetic retinopathy, allergic reactions, low blood sugar, and pancreatitis

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    Description

    CAS 910463-68-2

    production method: genetic engineering, expressed by E.Coli

    Molecular Formula:c187h291n45o59

    Molecular Weight:4113.58

    Sequence

    Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH

    Type: API

    Grade Standard: Pharma Grade

    Brand Name:zabcbio

    Model Number: ABC206

    water content≤5%

    TFA content≤1%

    Purity ≥ 98%;
    individual impurity≤1%

    assay(as is basis)≥90%;
    Storage Temperature 2-8℃;
    Packing Size 1G/Bottle, 10G/Bottle,50G/Bottle or at customers’ requirement.
    COA: Available

    Semaglutide host and Semaglutide side chain are available

    On sale: products or technology transfer fee

    Semaglutide API is a medication for the treatment of type 2 diabetes. Side effects include medullary thyroid cancer, kidney problems, diabetic retinopathy, allergic reactions, low blood sugar, and pancreatitis

    Function: Semaglutide is for the treatment of diabetes type 2.

    For research use only. We do not sell to patients.

    Advantages

    At present, our main expression system is fusion and tandem copy method expression, polypeptides with other special functions enzyme expressed syncretic by repeated tandem expression, so that the product has a high expression level and avoids the toxicity caused by chemical synthesis.

    Our unique and independent expression system established by our R&D team has been successful tested under the condition of 150L scale, it proves a high-density fermentation process can be industrially Large-scale applicated. The protease produced by self-expression can obtain more than 95% enzyme digestion efficiency, propeptide treatment, intermediate peptide purification, fat chain modification, fine purification, and raw material preparation process.

    The purity of the raw material dry powder is not less than 99%. The HPLC retention time and mass spectrometry molecular weight of the drug substance developed by us are completely consistent with the Novo Nordisk Victoza.

    Third-party lab-tested The cell viability in vitro and PK & PD determination in monkeys, the pharmacokinetics, EC50, and glucagon control effect are consistent with the Novo Nordisk Rybelsus.

    according to 18mg: 3.0ml injection, one kilogram of raw materials can produce 50,000 tablets.

     

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