Description
Form: Powder
M.wt:433.95
Formula: C18H28ClN3O5S
Grade: Pharma Grade
CAS No.: 747-36-4
Brand: zabcbio
COA: Available
Sample: Free Sample
Shelf Life: 2 Years
Purity:≥99% (HPLC)
Origin: China
PH(10% w/v):3.5-5.5
Loss on drying: 2.0% MAX
Heavy Metals: NMT 20ppm
Guarantee: Full refund if you met any quality problem
Storage：Store in sealed containers at cool & dry place, Protect from light, moisture and pest infestation.
Lead time: depends on quantity
| Items | Specification | Results |
| Appearance | White Crystalline Powder | Complies |
| Melting point | ABOUT 240 DEG C | 239.0 DEG C |
| Identification | UV,IR SULFATE TEST | Complies |
| ACIDITY | 3.5-5.5 | 3.66 |
| CLARITY OF SOLUTION | NOT MORE THAN SLIGHTLY TURBID | Complies |
| CLARITY OF SOLUTION | NOT MORE THAN SLIGHTLY YELLOW | Complies |
| LEAD | ≤20 PPM | <20ppm |
| CHLORIDE | ≤350 PPM | <350ppm |
| Related substances | NOT MORE THAN 1 SPOT ≥0.025%(W/V) NO SPOTS≥0.05%(W/V) TOTAL≤2.0% | Complies |
| ORDINARY IMPURITIES | MEETS THE REQUIREMENTS | Complies |
| Loss on drying | 2.0% MAX | 0.17% |
| SULPHATED ASH | 0.2% MAX | 0.05% |
| Assay | 98-102% | 99.6% |
| ORGANIC VOLATILE IMPURITIES ETHAN0L | 2000 PPM MAX | 1100 PPM |
| ETHYL ACETATE | 2000 PPM MAX | 53 PPM |
| CONCLUSION | COMPLIES WITH REQUIREMENT BP2019/USP41 |
What is Hydroxychloroquine sulfate?
Hydroxychloroquine sulfate is an antimalarial drug that also has anti-inflammatory, immunomodulatory and anticoagulant effects.
At present, hydroxychloroquine is mainly used in the clinical treatment of rheumatoid arthritis, juvenile chronic arthritis, discoid lupus erythematosus, and systemic erythema. Lupus, but the onset of clinical effect is slow, it usually takes 2 to 4 months.
The pharmacological effects of this drug are not very clear. It may be related to stabilizing the lysosomal membrane, inhibiting the formation of prostaglandins, inhibiting the chemotactic of polymorphonuclear cells and the role of phagocytic cells, and may interfere with monocyte interleukin- 1 formation and inhibition of neutrophil superoxide release.
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