aFGF Fibroblast Growth Factor Acidic Wholesale

CAS No.
106096-92-8

Other Names
rh-aFGF, aFGF,FGF-1,FGF-alpha, Fibroblast Growth Factor-Acidic (rh-aFGF)/afgf/Sh-polypeptide-11

Molecular Formula.
Molecular Weight:  16.0 kDa

Resources
Yeast

Place of Origin
China (Mainland)

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    Description

    Fibroblast Growth FactorAcidic (aFGF), also known as FGF1, is a member of the fibroblast growth factor (FGF) family.

    FGF acidic is a potent mitogenic agent for a wide variety of mesodermderived cells including BALB/c 3T3 fibroblasts, capillary and endocardial endothelial cells, myoblasts, vascular smooth muscle cells, mesothelial cells, glial cells, and adrenal cortex cells.

    It has a wide range of biological effects and potential clinical applications.

    FGF acidic has the ability of binding to heparin. And heparin potentiates the actions of aFGFas well as its stability against high temperature, extreme pH degeneration and hydrolysis.

    RhaFGF is a  single and nonglycosylated polypeptide chain containing 141 amino acids and having a molecular mass of 16 kDa expressed by yeast.

    Type

    Grade Standard: Cosmetic Grade

    Brand Name: ZABCbio

    Model Number: ABC107

    Purity: 96.0%  Test Method:  SDS-PAGE

    Biological Activity: 2000000IU/mg

    Shelf life:3 Years Proper Storage

    Heavy Metals:≤10 PPM

    Appearance: White crystalline powder

    Packing:1G/Bottle, 10G/Bottle,50G/Bottle or at customers requirements.

    HS Code:29349930

    Function

      afgf

    Anti-wrinkle and Anti-aging

    • aEGF modulates the skin rejuvenating by kstimulation of cell proliferation
    • aEGF rejuvenates both the epidermal cells and the underlying fibroblast cells, which produce collagen, elastin, and hyaluronic acid, maintain human skin elasticity, and decrease cutaneous senescence.
    • The proliferation of epidermal cells enhanced the skin cells regeneration.

    Wound healing and tissue repair

    Angiogenic in vivo, stimulate cell proliferation on human vein endothelial cell, induce the formation of new capillary blood vessels. It binds to heparin, which potentiates its biological activity and protects it from proteolysis.

    Rejuvenates hair follicle to produce new hair

    aFGF can activate FGF-7, promote hair growth by stimulation of cell proliferation on primary hair cell, treat or prevent baldness.

    Mitogenic for a variety of mesenchymal and neuroectodermal cells

    It promotes DNA synthesis, stimulate cell proliferation and differentiation associated with wound healing, angiogenesis, tissue regeneration, embryogenesis and CNS development.

     

    Interactions

    Alcohol and iodine may probably destroy the characteristic properties of aFGF which lead to the decrease of its activity.

    The skin on which Alcohol or iodine are used should be washed with normal saline prior to apply aFGF.

     

    Advantage

    Fast repair of burn wounds, scratches, burns, falls and other fresh wounds.

    Redness, freckle and skin repair after the damaged skin

    hotorejuvenation after the rapid repair of damaged skin

    Faster delivery

    1. Sample order in stock and 14 days for bulk production.
    2. Our biological factors are made by our own pharmaceutical factory, not cosmetic plant.
    3. 60 Days Warranty of quality of goods.

     

    FAQ

    Q:How to store the product?

    A:Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles and exposure to frequent temperature change

    Q:What is packing details:

    A:1mg , 10mg , 100mg , 1g

    Q: What’s the lead time

    A:10 days

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